Detecting Hydroxychloroquine Retinal Toxicity using a Novel Multifocal Electroretinography Stimulus
نویسندگان
چکیده
منابع مشابه
Retina in rheumatic diseases: standard full field and multifocal electroretinography in hydroxychloroquine retinal dysfunction.
BACKGROUND The purpose of this study was to evaluate and compare full-field electroretinography (ERG) and multifocal electroretinography (mfERG) results in detecting retinal dysfunction in a large number of asymptomatic patients treated with hydroxychloroquine (Hy). METHODS Fifty eyes in 50 patients with rheumatic diseases who had been using Hy for a period of time ranging from 30 months to 1...
متن کاملNoninvasive assessment of retinal function in rats using multifocal electroretinography.
PURPOSE To assess the applicability of multifocal electroretinograms (mfERGs) for evaluation of function in this small-eyed animal with a rod-dominant retina that is often used to model retinal diseases. METHODS Noninvasive monocular mfERGs were recorded in anesthetized albino (Sprague-Dawley) and pigmented (Long Evans) rats. Achromatic stimuli subtending a 49 degrees by 53 degrees field cons...
متن کاملThe use of multifocal electroretinography in the assessment of retinal toxicity caused by pharmacological agents
Multifocal electroretinography (mfERG) was developed by Sutter and Tran1 and has since revolutionized objective functional assessment of retinal diseases. In contrast to full-field electroretinography (ERG), which measures the electrical activity of the entire retina, mfERG allows simultaneous measurements of multiple responses at different retinal locations, thus enabling topographic mapping o...
متن کاملRETINAL DISORDERS Comparison of different screening methods for chloroquine/ hydroxychloroquine retinopathy: multifocal electroretinography, color vision, perimetry, ophthalmoscopy, and fluorescein angiography
Purpose To compare various screening methods for the early diagnosis of retinal dysfunction in patients with long-term chloroquine (CQ) and hydroxychloroquine (HCQ) treatment. Methods Twenty patients with long-term CQ/HCQ treatment underwent ophthalmologic evaluation including visual acuity testing, ophthalmoscopy, fluorescein angiography, color vision tests, visual field and multifocal electro...
متن کاملRetinal toxicity in long term hydroxychloroquine treatment.
OBJECTIVE To report clinical experience from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) who were receiving recommended doses of hydroxychloroquine for more than six years, and were monitored for evidence of hydroxychloroquine related retinopathy every six months. METHODS A prospective (and continuing) evaluation was made of the potential retinal toxicity of...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2019
ISSN: 1755-375X,1755-3768
DOI: 10.1111/j.1755-3768.2019.5370